Françoise-Catherine Fabre was born on 22 April 1811 in Saint-Geniez d'Olt, in Cantal (France), into a large family of modest economic conditions. She spent her childhood and adolescence in St. Martial until he was 19, helping her parents care of the house and her younger siblings. During these years, she often prayed in the small sanctuary of Chaudes-Aigues (a few kilometers from St Martial) before the statue of the Virgin of Pity. She is conquered by his humble and silent gesture that gives the life less Son to humanity. And this is how a simple and profound faith takes shape in Françoise-Catherine and the desire to give herself completely to God begins to grow in her heart

On 14 September 1830 she joined, as a novice, the flourishing Fraternity of Dominican Third Order in Chaudes-Aigues.
In May 1831 she made her profession with the name of Sr. Marguerite Gérine. She moved to Chaudes-Aigues where, together with other sisters, she lived from her work, visited and assisted the sick; she used her savings —often the fruit of personal sacrifice—to help the poor and suffering.

At the beginning of 1842, Sr. Gérine settled in Toulouse with seven other tertiary sisters, including two blood sisters. She was appointed superior of this community which was dedicated to caring for the sick at home. She was supported by Fr. Lacordaire who recognized in her the same spirit as Saint Dominic

In these years Sr. Gèrine opened other communities: in Tarbes, in Carcassonne, in Pau.
At the end of August 1852, after several requests from the mayor, Sr. Gérine moved - with two other sisters - to Albi to open community there. It is the first House of the Congregation; in fact, on 2 September 1852, Sr. Gérine received the official recognition of her Congregation from the Archbishop of Albi.
In 1854, in Albi, Sr. Gérine purchased the Congregation's first house on land that had once housed a Dominican convent, which was later destroyed during the French Revolution. The sisters therefore moved from “Rue du College” to “Rue du Seminaire”

New communities continued to arise one after another; Sr. Gérine – now “Mother” – continues to give life to her religious Family and make it grow.

In December 1862, at the invitation of Napoleon III, three sisters settled in Italy in Civitanova Marche, to dedicate themselves to the education of children and the care of elderly people.
The following year Mother Gérine went to Rome to meet Pope Pius IX. Prostrated at his feet, she received his lovely words into her heart: «Go, my daughter, and work to extend your Institute as much as you can».

El 25 de septiembre de 1865, la Madre Gérine fue nombrada Superiora general vitalicia por el P. Saudreau, Prior provincial de los frailes dominicos de Toulouse.
En 1872 entraron en vigor las Constituciones aprobadas por elarzobispo de Albi. En los últimos años, las comunidad estambién se han multiplicado en Italia. En 1874 la Madre Gerine envió un pequeño grupo de hermanas a Uruguay y de allí a Argentina.

For reasons that are still not entirely clear today, Mother Gérine resigned from her leadership of the Congregation. For a short time she remained in Albi and later moved to the community of Carcassonne.

Mother Gérine ends her earthly existence in Carcassonne, surrounded by the sisters of the community, after years spent in prayer, in silent service, in the unconditional acceptance of the mystery of the Cross, as a profound act of faith. She died begging: «Albí... Albí...».